A multicenter case control study of association of vitamin D with breast cancer among women in Karachi, Pakistan.

ABSTRACT: BACKGROUND:The prevalence of vitamin D inadequacy and breast cancer are both high among women living in Karachi, Pakistan. METHODS:A matched case control study was conducted in two hospitals of Karachi, Pakistan to evaluate the association of vitamin D (serum 25-hydroxyvitamin D) concentrations, vitamin D supplementation and sun exposure with breast cancer among Pakistani women. A total of 411 newly diagnosed histologically confirmed primary breast cancer cases were enrolled and 784 controls, free of breast and any other cancers, were matched by age (year of birth ± 5 years), residence in the same geographic area and study site. Information was collected on sociodemographic history, history of vitamin D supplementation, past medical and obstetrical history, family history of breast cancer,

SUBMITTER: Shamsi U 

PROVIDER: S-EPMC6975526 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature