Microbial succession during wheat bran fermentation and colonisation by human faecal microbiota as a result of niche diversification.

ABSTRACT: The human gut can be viewed as a flow-through system with a short residence time, a high turnover rate and a spatial gradient of physiological conditions. As a consequence, the gut microbiota is exposed to highly fluctuating environmental determinants presented by the host and diet. Here, we assessed the fermentation and colonisation of insoluble wheat bran by faecal microbiota of three individuals at an unprecedented sampling intensity. Time-resolved 16S rRNA gene amplicon sequencing, revealed a dynamic microbial community, characterised by abrupt shifts in composition, delimiting states with a more constant community, giving rise to a succession of bacterial taxa alternately dominating the community over a 72 h timespan. Early stages were dominated by Enterobacteriaceae and Fusobacterium

SUBMITTER: De Paepe K 

PROVIDER: S-EPMC6976558 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature