3D printed mold leachates in PDMS microfluidic devices.

ABSTRACT: The introduction of poly(dimethylsiloxane) (PDMS) and soft lithography in the 90's has revolutionized the field of microfluidics by almost eliminating the need for a clean-room environment for device fabrication. More recently, 3D printing has been introduced to fabricate molds for soft lithography, the only step for which a clean-room environment is still often necessary, to further support the rapid prototyping of PDMS microfluidic devices. However, toxicity of most of the commercial 3D printing resins has been established, and little is known regarding the potential for 3D printed molds to leak components into the PDMS that would, in turn, hamper cells and/or tissues cultured in the devices. In the present study, we investigated if 3D printed molds produced by stereolithography can leac

SUBMITTER: de Almeida Monteiro Melo Ferraz M 

PROVIDER: S-EPMC6976631 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature