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Co-circulation of multiple enterovirus D68 subclades, including a novel B3 cluster, across Europe in a season of expected low prevalence, 2019/20.

ABSTRACT: Enterovirus D68 (EV-D68) was detected in 93 patients from five European countries between 1 January 2019 and 15 January 2020, a season with expected low circulation. Patients were primarily children (n = 67, median age: 4 years), 59 patients required hospitalisation and five had severe neurologic manifestations. Phylogenetic analysis revealed two clusters in the B3 subclade and subclade A2/D. This circulation of EV-D68 associated with neurological manifestations stresses the importance of surveillance and diagnostics beyond expected peak years.

SUBMITTER: Midgley SE 

PROVIDER: S-EPMC6976881 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

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Co-circulation of multiple enterovirus D68 subclades, including a novel B3 cluster, across Europe in a season of expected low prevalence, 2019/20.

Midgley Sofie Elisabeth SE   Benschop Kimberley K   Dyrdak Robert R   Mirand Audrey A   Bailly Jean-Luc JL   Bierbaum Sibylle S   Buderus Stefan S   Böttcher Sindy S   Eis-Hübinger Anna-Maria AM   Hönemann Mario M   Jensen Veronika Vorobieva VV   Hartling Ulla Birgitte UB   Henquell Cécile C   Panning Marcus M   Thomsen Marianne Kragh MK   Hodcroft Emma B EB   Meijer Adam A  

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20200101 2

Enterovirus D68 (EV-D68) was detected in 93 patients from five European countries between 1 January 2019 and 15 January 2020, a season with expected low circulation. Patients were primarily children (n = 67, median age: 4 years), 59 patients required hospitalisation and five had severe neurologic manifestations. Phylogenetic analysis revealed two clusters in the B3 subclade and subclade A2/D. This circulation of EV-D68 associated with neurological manifestations stresses the importance of survei  ...[more]

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