Ontology highlight
ABSTRACT:
SUBMITTER: Jost D
PROVIDER: S-EPMC6977230 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Jost Daniel D Lemoine Sabine S Lemoine Frederic F Lanoe Vincent V Maurin Olga O Derkenne Clément C Franchin Frattini Marilyn M Delacote Maëlle M Seguineau Edouard E Godefroy Anne A Hervault Nicolas N Delhaye Ludovic L Pouliquen Nicolas N Louis-Delauriere Emilie E Trichereau Julie J Roquet Florian F Salomé Marina M Verret Catherine C Bihannic René R Jouffroy Romain R Frattini Benoit B Hong Tuan Ha Vivien V Dang-Minh Pascal P Travers Stéphane S Bignand Michel M Martinaud Christophe C Garrabe Eliane E Ausset Sylvain S Prunet Bertrand B Sailliol Anne A Tourtier Jean Pierre JP
Trials 20200122 1
<h4>Background</h4>Post-trauma bleeding induces an acute deficiency in clotting factors, which promotes bleeding and hemorrhagic shock. However, early plasma administration may reduce the severity of trauma-induced coagulopathy (TIC). Unlike fresh frozen plasma, which requires specific hospital logistics, French lyophilized plasma (FLYP) is storable at room temperature and compatible with all blood types, supporting its use in prehospital emergency care. We aim to test the hypothesis that by att ...[more]