Age-variant and age-invariant features of functional brain organization in middle-aged and older autistic adults.

ABSTRACT:

Background

The majority of research effort into autism has been dedicated to understanding mechanisms during early development. As a consequence, research on the broader life course of an autism spectrum condition (ASC) has largely been neglected and almost nothing is known about ASC beyond middle age. Differences in brain connectivity that arise during early development may be maintained across the lifespan and may play protective or detrimental roles in older age.

Method

This study explored age-related differences in functional connectivity across middle and older age in clinically diagnosed autistic adults (n = 44, 30-73 years) and in an age-matched typical comparison group (n = 45).

Results

The results indicated parallel age-related associations in A

SUBMITTER: Bathelt J 

PROVIDER: S-EPMC6977283 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature