Improved emotion regulation after neurofeedback: A single-arm trial in patients with borderline personality disorder.

ABSTRACT: Real-time functional magnetic resonance imaging (fMRI) neurofeedback training of amygdala hemodynamic activity directly targets a neurobiological mechanism, which contributes to emotion regulation problems in borderline personality disorder (BPD). However, it remains unknown which outcome measures can assess changes in emotion regulation and affective instability, associated with amygdala downregulation in a clinical trial. The current study directly addresses this question. Twenty-four female patients with a DSM-IV BPD diagnosis underwent four runs of amygdala neurofeedback. Before and after the training, as well as at a six-weeks follow-up assessment, participants completed measures of emotion dysregulation and affective instability at diverse levels of analysis (verbal report, clinical

SUBMITTER: Zaehringer J 

PROVIDER: S-EPMC6978219 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature