Reduced striatal activation in response to rewarding motor performance feedback after stroke.

ABSTRACT:

Introduction

Motor skill learning can help stroke survivors to cope with motor function deficits but requires many repetitions. One factor that keeps patients motivated is obtaining reward upon successfully completing a motor task. It has been suggested that stroke survivors have deficits in reward processing which may negatively impact skill learning.

Objective

To test the hypothesis that stroke survivors have deficient reward processing during motor skill learning evident in reduced activation in the striatum and its subdivisions in functional magnetic resonance imaging as compared with healthy, age-matched control subjects.

Methods

Striatal activity in response to performance dependent feedback and monetary reward was measured in 28 subacute stroke patients and 18

SUBMITTER: Widmer M 

PROVIDER: S-EPMC6978223 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature