Sleep disordered breathing in Marfan syndrome: Value of standard screening questionnaires.

ABSTRACT:

Background

A high prevalence of sleep disordered breathing (SDB) has been reported in persons with Marfan syndrome (MFS), a single gene disorder of connective tissue resulting in premature death from aortic rupture. The burden of SDB and accompanying hemodynamic stress could warrant broad screening in this population. Our goal was to assess the utility of traditional SDB screening tools in our sample of persons with MFS.

Methods

Participants were recruited during an annual Marfan Foundation meeting and Marfan status confirmed using the Ghent criteria. Screening questionnaires were administered and SDB assessed by home sleep testing. We assessed accuracy of screening tools using receiver-operating characteristic curve analyses.

Results

The prevalence of moderate-severe

SUBMITTER: Sowho MO 

PROVIDER: S-EPMC6978263 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature