Ontology highlight
ABSTRACT:
SUBMITTER: Burke EE
PROVIDER: S-EPMC6978526 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Nature communications 20200123 1
Human induced pluripotent stem cells (hiPSCs) are a powerful model of neural differentiation and maturation. We present a hiPSC transcriptomics resource on corticogenesis from 5 iPSC donor and 13 subclonal lines across 9 time points over 5 broad conditions: self-renewal, early neuronal differentiation, neural precursor cells (NPCs), assembled rosettes, and differentiated neuronal cells. We identify widespread changes in the expression of both individual features and global patterns of transcript ...[more]