Bioactive Proteins in Channa striata Promote Wound Healing through Angiogenesis and Cell Proliferation.

ABSTRACT:

Background

Channa striata are speculated to contain bioactive proteins with the ability to enhancing wound healing. It is commonly consumed after surgery for a faster recovery of the wound.

Objective

To identify the bioactive proteins and evaluate their ability in cell proliferation and angiogenesis promotion.

Material and methods

Freeze-Dried Water Extracts (FDWE) and Spray-Dried Water Extracts (SDWE) of C. striata were tested with MTT assay using EA.hy926 endothelial cell line and ex-vivo aortic ring assay. Later the proteins were fractionated and analysed using an LC-QTOF mass spectrometer. The data generated were matched with human gene database for protein similarity and pathway identification.

Results

Both samples have shown positive cell proliferation an

SUBMITTER: Kwan SH 

PROVIDER: S-EPMC6978642 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature