Clinical characteristics and prognostic value of MEX3A mRNA in liver cancer.

ABSTRACT:

Background

MEX3A is an RNA-binding proteins (RBPs) that promotes the proliferation, invasion, migration and viability of cancer cells. The aim of this study was to explore the clinicopathological characteristics and prognostic significance of MEX3A mRNA expression in liver cancer.

Methods

RNA-Seq and clinical data were collected from The Cancer Genome Atlas (TCGA). Boxplots were used to represent discrete variables of MEX3A. Chi-square tests were used to analyze the correlation between clinical features and MEX3A expression. Receiver operating characteristic (ROC) curves were used to confirm diagnostic ability. Independent prognostic ability and values were assessed using Kaplan-Meier curves and Cox analysis.

Results

We acquired MEX3A RNA-Seq from 50 normal liver tiss

SUBMITTER: Yang D 

PROVIDER: S-EPMC6979405 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature