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Real-World Effectiveness and Real-World Cost-Effectiveness of Intravitreal Aflibercept and Intravitreal Ranibizumab in Neovascular Age-Related Macular Degeneration: Systematic Review and Meta-Analysis of Real-World Studies.


ABSTRACT:

SUBMITTER: Carrasco J 

PROVIDER: S-EPMC6979459 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

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Real-World Effectiveness and Real-World Cost-Effectiveness of Intravitreal Aflibercept and Intravitreal Ranibizumab in Neovascular Age-Related Macular Degeneration: Systematic Review and Meta-Analysis of Real-World Studies.

Carrasco Joao J   Pietsch Georg-Alexander GA   Nicolas Marie-Pierre MP   Koerber Cecile C   Bennison Craig C   Yoon Jisu J  

Advances in therapy 20191114 1


<h4>Introduction</h4>Treatment of neovascular age-related macular degeneration (nAMD) has evolved with the advent of anti-vascular endothelial growth factor agents such that intravitreally administered aflibercept and ranibizumab (RBZ) have become the standard of care. Randomized clinical trials (RCTs) have demonstrated the benefits of these agents in nAMD; however, results achieved under RCT protocols may not always be replicated in clinical practice. Assessing real-world outcomes is important  ...[more]

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