Survival Disparities in Black Patients With EGFR-mutated Non-small-cell Lung Cancer.

ABSTRACT:

Background

Little is known about the difference between black and non-black patients with epidermal growth factor receptor (EGFR)-mutated non-small-cell lung cancer (NSCLC), particularly regarding survival. We thus characterized the EGFR expression profile, clinical characteristics, and survival outcome in these patients.

Patient and methods

We reviewed the cancer registry and patient charts at a New York-Bronx network (n = 2773) treating a large population of minority patients, for non-squamous NSCLC (n = 1986) diagnosed between 2009 and 2015. Survival was adjusted for smoking, gender, age, weight, and stage.

Results

The EGFR mutation rate was 15% (98/652) in tested patients (black, 14%; non-black, 16%). There was no significant difference between the 2 cohorts with

SUBMITTER: Cheng H 

PROVIDER: S-EPMC6980454 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature