Epidemiology of Hereditary Diseases in the Karachay-Cherkess Republic.

ABSTRACT: Prevalence and allelic heterogeneity of hereditary diseases (HDs) could vary significantly in different human populations. Current knowledge of HDs distribution in populations is generally limited to either European data or analyses of isolated populations which were performed several decades ago. Thus, an acknowledgement of the HDs prevalence in different modern open populations is important. The study presents the results of a genetic epidemiological study of hereditary diseases (HDs) in the population of the Karachay-Cherkess Republic (KChR). Clinical screening of a population of 410,367 people for the identification of HDs was conducted. The population surveyed is represented by five major ethnic groups-Karachays, Russians, Circassians, Abazins, Nogais. The study of the populations was

SUBMITTER: Zinchenko RA 

PROVIDER: S-EPMC6981994 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature