Selenium and bladder cancer risk: a meta-analysis.

ABSTRACT:

Background

Selenium is considered to be an antioxidant, and its high levels have been inversely associated with cancer risk of several sites. This meta-analysis examined the relationship between levels of selenium measured in serum and toenails, and the risk of bladder cancer.

Methods

A meta-analysis using data from seven published epidemiologic studies (three case-control, three nested case-control, one case-cohort) published before March 2010 was done to examine the association between levels of selenium and bladder cancer. Fixed and random effects analyses were done to calculate meta-odds ratio (mOR) and 95% confidence intervals (CI). Heterogeneity among studies was measured by the I(2) statistic.

Results

Overall, the risk of bladder cancer was inversely associated

SUBMITTER: Amaral AF 

PROVIDER: S-EPMC6982398 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature