Incidence and Risk Factors for Isolated Esophageal Cancer Recurrence to the Brain.

ABSTRACT:

Background

Recurrence of esophageal cancer in the brain is rare but associated with a poor prognosis. Identification of risk factors for isolated brain metastasis of esophageal cancer (iBMEC) after surgical treatment may guide surveillance recommendations to enable early identification and intervention before widespread metastasis.

Methods

Patients with iBMEC (n = 38) were identified from a prospective database of patients with esophageal cancer who underwent esophagectomy. Risk factors for iBMEC were identified using competing risk regression analysis.

Results

In a cohort of 1760 patients, 39% recurred and iBMEC developed in 2% by the end of the study. Survival in patients with iBMEC was similar to survival in patients with distant recurrence (median overall survival

SUBMITTER: Nobel TB 

PROVIDER: S-EPMC6982555 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature