CEST MRI quantification procedures for breast cancer treatment-related lymphedema therapy evaluation.

ABSTRACT:

Purpose

To quantify chemical exchange saturation transfer contrast in upper extremities of participants with lymphedema before and after standardized lymphatic mobilization therapy using correction procedures for B₀ and B₁ heterogeneity, and T₁ relaxation.

Methods

Females with (n = 12) and without (n = 17) breast cancer treatment-related lymphedema (BCRL) matched for age and body mass index were scanned at 3.0T MRI. B₁ efficiency and T₁ were calculated in series with chemical exchange saturation transfer in bilateral axilla (B₁ amplitude = 2µT, Δω = ±5.5 ppm, slices = 9, spatial resolution = 1.8 × 1.47 × 5.5 mm³ ). B₁ dispersion measurements (B₁ = 1-3 µT; increment = 0.5 µT) we

SUBMITTER: Crescenzi R 

PROVIDER: S-EPMC6982565 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature