Trabecular bone imaging using a 3D adiabatic inversion recovery prepared ultrashort TE Cones sequence at 3T.

ABSTRACT:

Purpose

To investigate direct imaging of trabecular bone using a 3D adiabatic inversion recovery prepared ultrashort TE cones (3D IR-UTE-Cones) sequence.

Methods

The proposed 3D IR-UTE-Cones sequence used a broadband adiabatic inversion pulse together with a short TR/TI combination to suppress signals from long T₂ tissues such as muscle and marrow fat, followed by multispoke UTE acquisition to detect signal from short T₂ water components in trabecular bone. The feasibility of this technique for robust suppression of long T₂ tissues was first demonstrated through numerical simulations. The proposed IR-UTE-Cones sequence was applied to a hip agarose bone phantom and to 6 healthy volunteers for morphologic and quantitative T2∗ and proton density

SUBMITTER: Ma YJ 

PROVIDER: S-EPMC6982597 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature