Genetically Engineered Bacterial Biohybrid Microswimmers for Sensing Applications.

ABSTRACT: Bacterial biohybrid microswimmers aim at exploiting the inherent motion capabilities of bacteria (carriers) to transport objects (cargoes) at the microscale. One of the most desired properties of microswimmers is their ability to communicate with their immediate environment by processing the information and producing a useful response. Indeed, bacteria are naturally equipped with such communication skills. Hereby, two-component systems (TCSs) represent the key signal transducing machinery and enable bacteria to sense and respond to a variety of stimuli. We engineered a natural microswimmer based on the Gram-positive model bacterium Bacillus subtilis for the development of biohybrids with sensing abilities. B. subtilis naturally adhered to silica particles, giving rise to diff

SUBMITTER: Sun Z 

PROVIDER: S-EPMC6982730 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature