Prenatal Primary Prevention of Mental Illness by Micronutrient Supplements in Pregnancy.

ABSTRACT: Genes, infection, malnutrition, and other factors affecting fetal brain development are a major component of risk for a child's emotional development and later mental illnesses, including schizophrenia, bipolar disorder, and autism. Prenatal interventions to ameliorate that risk have yet to be established for clinical use. A systematic review of prenatal nutrients and childhood emotional development and later mental illness was performed. Randomized trials of folic acid, phosphatidylcholine, and omega-3 fatty acid supplements assess effects of doses beyond those adequate to remedy deficiencies to promote normal fetal development despite genetic and environmental risks. Folic acid to prevent neural tube defects is an example. Vitamins A and D are currently recommended at maximum levels, but

SUBMITTER: Freedman R 

PROVIDER: S-EPMC6984656 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature