Impact of periodontal treatment on the RANKL/OPG ratio in crevicular fluid.

ABSTRACT:

Aim

Alveolar resorption is one of the most important events in periodontitis. Osteoclast activity is regulated by the ratio between receptor activator of NF-κB ligand (RANKL) and osteoprotegerin (OPG). The aim of this study was to evaluate changes in the RANKL/OPG ratio in crevicular fluid after periodontal treatment.

Material and methods

A total of 15 patients with periodontitis were included in the study group. Samples were collected from an area with active periodontitis and a healthy area. The RANKL and OPG levels were measured before and after periodontal scaling and root planing (SRP) treatment. The study group was compared to the control group, which included 10 patients without periodontitis. ID Clinicaltrial.gov: NCT03787875.

Results

A decrease in the RANKL l

SUBMITTER: Lopez Roldan A 

PROVIDER: S-EPMC6984681 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature