NAPAbench 2: A network synthesis algorithm for generating realistic protein-protein interaction (PPI) network families.

ABSTRACT: Comparative network analysis provides effective computational means for gaining novel insights into the structural and functional compositions of biological networks. In recent years, various methods have been developed for biological network alignment, whose main goal is to identify important similarities and critical differences between networks in terms of their topology and composition. A major impediment to advancing network alignment techniques has been the lack of gold-standard benchmarks that can be used for accurate and comprehensive performance assessment of such algorithms. The original NAPAbench (network alignment performance assessment benchmark) was developed to address this problem, and it has been widely utilized by many researchers for the development, evaluation, and comp

SUBMITTER: Woo HM 

PROVIDER: S-EPMC6984706 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature