Survival in Locally Advanced Pancreatic Cancer After Neoadjuvant Therapy and Surgical Resection.

ABSTRACT:

Objective

The aim of the study was to identify the survival of patients with locally advanced pancreatic cancer (LAPC) and assess the effect of surgical resection after neoadjuvant therapy on patient outcomes.

Background

An increasing number of LAPC patients who respond favorably to neoadjuvant therapy undergo surgical resection. The impact of surgery on patient survival is largely unknown.

Materials and methods

All LAPC patients who presented to the institutional pancreatic multidisciplinary clinic (PMDC) from January 2013 to September 2017 were included in the study. Demographics and clinical data on neoadjuvant treatment and surgical resection were documented. Primary tumor resection rates after neoadjuvant therapy and overall survival (OS) were the primary study e

SUBMITTER: Gemenetzis G 

PROVIDER: S-EPMC6985003 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature