Health and work disability outcomes in parents of patients with schizophrenia associated with antipsychotic exposure by the offspring.

ABSTRACT: This study aimed to identify if antipsychotic exposure in offspring is associated with psychiatric and non-psychiatric healthcare service use and work disability of their parents. This Swedish population-based cohort study was based on data comprising 10,883 individuals with schizophrenia, who had at least one identifiable parent in the nationwide registers, and their parents (N = 18,215). The register-based follow-up during 2006-2013 considered the level of antipsychotic exposure and persistence of use of the offspring, further categorized into first (FG) and second generation (SG) antipsychotics, and orals versus long-acting injections (LAIs). The main outcome measure was parental psychiatric healthcare service use, secondary outcomes were non-psychiatric healthcare use and long-term sic

SUBMITTER: Taipale H 

PROVIDER: S-EPMC6985214 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature