Probiotics and Maternal Mental Health: A Randomised Controlled Trial among Pregnant Women with Obesity.

ABSTRACT: Poor maternal mental health has been associated with a myriad of pregnancy and child health complications. Obesity in pregnancy is known to increase one's risk of experiencing poor maternal mental health and associated physical and mental health complications. Probiotics may represent a novel approach to intervene in poor mental health and obesity. We conducted this pre-specified secondary analysis of the Healthy Mums and Babies (HUMBA) randomised controlled trial to investigate whether probiotics would improve maternal mental health outcomes up to 36 weeks of pregnancy. Two-hundred-and-thirty pregnant women with obesity (BMI ≥ 30.0 kg/m²) were recruited and randomised to receive probiotic (Lactobacillus rhamnosus GG and Bifidobacterium lactis BB12, minimum 6.5 × 10⁹

SUBMITTER: Dawe JP 

PROVIDER: S-EPMC6987087 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature