Exposure to Bisphenol A and phthalates metabolites in the third trimester of pregnancy and BMI trajectories.

ABSTRACT:

Background

Bisphenol A (BPA) and phthalates metabolites are linked to a variety of adverse health consequences but studies have not explored their association with growth trajectories.

Objective

Explore body mass index (BMI) trajectories for tertile exposures to BPA and phthalates metabolites in the third trimester of pregnancy.

Methods

We constructed BMI (kg/m² ) trajectories from birth to 14 years in a birth cohort of 249 children from Mexico City using tertiles of third trimester maternal urinary concentrations of BPA and phthalates metabolites. Fractional age polynomials and mixed effects models were fit separately by sex. Predicted models were plotted for each metabolite tertile with the covariates mother's education and BMI centered at average values.

SUBMITTER: Yang TC 

PROVIDER: S-EPMC6988102 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature