The evolutionary arms race between transposable elements and piRNAs in Drosophila melanogaster.

ABSTRACT:

Background

The piwi-interacting RNAs (piRNAs) are small non-coding RNAs that specifically repress transposable elements (TEs) in the germline of Drosophila. Despite our expanding understanding of TE:piRNA interaction, whether there is an evolutionary arms race between TEs and piRNAs was unclear.

Results

Here, we studied the population genomics of TEs and piRNAs in the worldwide strains of D. melanogaster. By conducting a correlation analysis between TE contents and the abundance of piRNAs from ovaries of representative strains of D. melanogaster, we find positive correlations between TEs and piRNAs in six TE families. Our simulations further highlight that TE activities and the strength of purifying selection against TEs are important factors shaping the interactions between

SUBMITTER: Luo S 

PROVIDER: S-EPMC6988346 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature