Ontology highlight
ABSTRACT:
SUBMITTER: Wu T
PROVIDER: S-EPMC6988368 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Clinical epigenetics 20200128 1
<h4>Background</h4>5-Hydroxymethylcytosine (5hmC) is a novel epigenetic mark and may be involved in the mechanisms of tumorigenesis and malignant transformation. However, the role of 5hmC in ependymoma, the third most common brain tumor in children, remains unclear. The aim of this study sought to identify the characterization of 5hmC levels in pediatric posterior fossa ependymoma and to evaluate whether 5hmC levels could be a potential factor to predict clinical outcomes.<h4>Results</h4>Our res ...[more]