It's Absolutely Relative: The Effect of Age on the BMI-Mortality Relationship in Postmenopausal Women.

ABSTRACT:

Objective

The use of relative and absolute effect estimates has important implications for the interpretation of study findings. Likewise, examining additive and multiplicative interaction can lead to differing conclusions about the joint effects of two exposure variables. The aim of this paper is to examine the relationship between BMI and mortality on the relative and absolute scales and investigate interaction between BMI and age.

Methods

Data from 68,132 participants in the Women's Health Initiative (WHI) study were used. The risk ratio and risk difference of BMI on mortality were estimated. A product term was also included to examine interaction between BMI and age on the multiplicative scale, and the relative excess risk of interaction was calculated to measure additiv

SUBMITTER: Banack HR 

PROVIDER: S-EPMC6989046 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature