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Enantioselective catalytic synthesis of α-aryl-α-SCF₃-β^2,2-amino acids.

ABSTRACT: We herein report a novel entry towards chiral α-SCF3-β2,2-amino acids by carrying out the ammonium salt-catalyzed α-trifluoromethylthiolation of isoxazolidin-5-ones. This approach allowed for high enantioselectivities and high yields and the obtained heterocycles proved to be versatile platforms to access other targets of potential interest.

SUBMITTER: Eitzinger A

PROVIDER: S-EPMC6989214 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

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Enantioselective catalytic synthesis of α-aryl-α-SCF₃-β^2,2-amino acids.

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Dataset Information

Enantioselective catalytic synthesis of α-aryl-α-SCF3-β2,2-amino acids.

OmicsDI is part of the ELIXIR infrastructure

Tweets

Enantioselective catalytic synthesis of α-aryl-α-SCF₃-β^2,2-amino acids.