Patient-reported outcomes in a large North American cohort living with chronic hepatitis B virus: a cross-sectional analysis.

ABSTRACT:

Background

Patient-reported outcomes (PROs) such as health-related quality of life (HRQoL) and symptoms associated with chronic hepatitis B viral (HBV) infection have not been well-described in North American cohorts.

Aims

To evaluate several PROs and associations with HBV disease activity markers.

Methods

Cross-sectional analysis including 876 adults who completed PRO measures during the Hepatitis B Research Network Adult Cohort Study. Participants on HBV treatment were excluded. Outcomes included: HRQoL using the SF-36 mental component summary and physical component summary scores; symptom burden using a 10-item Total Symptom Checklist and fatigue using an instrument from the Patient-Reported Outcomes Measurement Information System®. Covariates included laboratory m

SUBMITTER: Evon DM 

PROVIDER: S-EPMC6989387 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature