Ontology highlight
ABSTRACT:
SUBMITTER: Williams CB
PROVIDER: S-EPMC6989402 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Williams Carly B CB Phelps-Polirer Kendall K Dingle Ivan P IP Williams Christina J CJ Rhett Matthew J MJ Eblen Scott T ST Armeson Kent K Hill Elizabeth G EG Yeh Elizabeth S ES
Oncogene 20191009 5
Epidermal growth factor receptor (EGFR) is commonly over-expressed in metastatic breast cancer yet metastatic breast cancer is generally resistant to anti-EGFR therapies, and the mechanism for resistance to EGFR inhibitors in this setting is not fully understood. Hormonally up-regulated neu-associated kinase (HUNK) kinase is up-regulated in aggressive breast cancers and is thought to play a role in breast cancer metastasis. However, no studies have been conducted to examine a relationship betwee ...[more]