Maternal serum pentraxin 3 level in early pregnancy for prediction of gestational diabetes mellitus.

ABSTRACT:

Background

Our study aimed to reveal the relationship of maternal pentraxin 3 (PTX3)'s serum concentrations in early pregnancy with gestational diabetes mellitus (GDM) and to explore its potential in the prediction of GDM.

Methods

Totally 824 pregnant women were enrolled and divided into a GDM group and a normal glucose tolerance (NGT) group, whose maternal fasting serum PTX3 levels, plasma glucose and insulin were collected. The beta cell function index and quantitative insulin sensitivity check index (QUICKI) was calculated and a homeostatic model assessment of insulin resistance (HOMA-IR) was used with SPSS 22 software used for statistical analysis.

Results

Of all subjects, 13.59% developed GDM. Compared to the NGT group, the PTX3 level was increased in the GDM gro

SUBMITTER: Qu X 

PROVIDER: S-EPMC6990028 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature