Association between metabolic syndrome and prognosis of breast cancer: a meta-analysis of follow-up studies.

ABSTRACT:

Background

Metabolic syndrome (MetS) has been suggested to be a risk factor for many cancers, including breast cancer. However, it remains unclear whether MetS predicts poor prognosis in women with breast cancer. A meta-analysis was performed to summarize the association between MetS and clinical outcome in women with breast cancer.

Methods

Cohort studies were identified by search of PubMed and Embase databases. A random-effect model incorporating the potential heterogeneity was applied to pool the results. Subgroup analyses according to the ethnicity and study design were performed.

Results

Nine cohort studies with 17,892 women with breast cancer were included. Pooled results showed that MetS was significantly associated with an increased risk of breast cancer recurr

SUBMITTER: Li P 

PROVIDER: S-EPMC6990514 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature