Methods of competing risks flexible parametric modeling for estimation of the risk of the first disease among HIV infected men.

ABSTRACT:

Background

Patients infected with the Human Immunodeficiency Virus (HIV) are susceptible to many diseases. In these patients, the occurrence of one disease alters the chance of contracting another. Under such circumstances, methods for competing risks are required. Recently, competing risks analyses in the scope of flexible parametric models have risen to address this requirement. These lesser-known analyses have considerable advantages over conventional methods.

Methods

Using data from Multi Centre AIDS Cohort Study (MACS), this paper reviews and applies methods of competing risks flexible parametric models to analyze the risk of the first disease (AIDS or non-AIDS) among HIV-infected patients. We compared two alternative subdistribution hazard flexible parametric models (S

SUBMITTER: Nouri S 

PROVIDER: S-EPMC6990537 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature