An open-source video tracking system for mouse locomotor activity analysis.

ABSTRACT: OBJECTIVE:The ability to accurately and efficiently quantify mouse locomotor activity is essential for evaluating therapeutic efficacy and phenotyping genetically modified mice, in particular for the research of neuromuscular diseases. Our objective is to develop a program for video tracking of mice and locomotion analysis. RESULTS:Here we describe a MATLAB program for video tracking of mice and locomotion analysis. The system is composed of a webcam, an open field, and a computer with MATLAB installed. Animal behavior is recorded by the webcam and the video is then analyzed for mouse position on each frame by a customized MATLAB code. The system has been tested for analyzing two or more mice simultaneously placed in individual chambers. The accumulative moving distance, velocity and thigm

SUBMITTER: Zhang C 

PROVIDER: S-EPMC6990588 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature