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Association of Cognitive and Behavioral Features Between Adults With Tuberous Sclerosis and Frontotemporal Dementia.


ABSTRACT:

Importance

Individuals with tuberous sclerosis complex can develop a progressive neuropsychiatric syndrome known as tuberous sclerosis-associated neuropsychiatric disorders. Tuberous sclerosis-associated neuropsychiatric disorders symptoms overlap with clinical criteria for frontotemporal dementia, yet the association between the 2 has not been explored.

Objective

To investigate the potential association between tuberous sclerosis-associated neuropsychiatric disorders and frontotemporal dementia.

Design, setting, and participants

Case-control study that enrolled patients with tuberous sclerosis complex with normal IQs in an observational clinical study at the University of California, San Francisco, from 2017 to 2019 where they underwent a comprehensive clinical evalu

SUBMITTER: Liu AJ 

PROVIDER: S-EPMC6990672 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature