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Assessment of Extubation Readiness Using Spontaneous Breathing Trials in Extremely Preterm Neonates.


ABSTRACT:

Importance

Spontaneous breathing trials (SBTs) are used to determine extubation readiness in extremely preterm neonates (gestational age ≤28 weeks), but these trials rely on empirical combinations of clinical events during endotracheal continuous positive airway pressure (ET-CPAP).

Objectives

To describe clinical events during ET-CPAP and to assess accuracy of comprehensive clinical event combinations in predicting successful extubation compared with clinical judgment alone.

Design, setting, and participants

This multicenter diagnostic study used data from 259 neonates seen at 5 neonatal intensive care units from the prospective Automated Prediction of Extubation Readiness (APEX) study from September 1, 2013, through August 31, 2018. Neonates with birth weight less th

SUBMITTER: Shalish W 

PROVIDER: S-EPMC6990705 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature