Diagnosis Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Syndrome.

ABSTRACT:

Importance

Atypical parkinsonian syndromes (APS), including progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), and multiple system atrophy (MSA), may be difficult to distinguish in early stages and are often misdiagnosed as Parkinson disease (PD). The diagnostic criteria for PSP have been updated to encompass a range of clinical subtypes but have not been prospectively studied.

Objective

To define the distinguishing features of PSP and CBS subtypes and to assess their usefulness in facilitating early diagnosis and separation from PD.

Design, setting, participants

This cohort study recruited patients with APS and PD from movement disorder clinics across the United Kingdom from September 1, 2015, through December 1, 2018. Patients with APS were stratifie

SUBMITTER: Jabbari E 

PROVIDER: S-EPMC6990759 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature