Expanding Heart Transplant in the Era of Direct-Acting Antiviral Therapy for Hepatitis C.

ABSTRACT:

Importance

For patients awaiting heart transplant, hepatitis C-positive donors offer an opportunity to expand the donor pool, shorten wait times, and decrease wait-list mortality. While early reported outcomes among few heart transplant recipients have been promising, knowledge of 1-year outcomes in larger cohorts of patients is critical to shared decision-making with patients about this option.

Objective

To better define the association of hepatitis C-positive donors with heart transplant volumes, wait-list duration, the transmission and cure of donor-derived hepatitis C, and morbidity and mortality at 1 year.

Design, setting, and participants

This was a prospective, single-center observational study of 80 adult (age 18 years or older) patients who underwent heart tr

SUBMITTER: Schlendorf KH 

PROVIDER: S-EPMC6990812 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature