Noncutaneous and Cutaneous Cancer Risk in Patients With Atopic Dermatitis: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

Impaired skin barrier and aberrant immune function in atopic dermatitis (AD) may alter immune response to malignant cancer. Conflicting data exist on the risk of cancer in patients with AD.

Objective

To assess the risk of noncutaneous and cutaneous cancers in patients with AD compared with the general population without AD.

Data sources

Studies identified from searches of MEDLINE and Embase that were published from 1946 and 1980, respectively, to January 3, 2019. The following search terms were used: [(exp NEOPLASMS/ OR neoplas*.tw. OR tumo*.tw. OR cancer*.tw. OR malignanc*.tw.) AND (exp Dermatitis, Atopic/ OR (atopic adj1 (dermatit* or neurodermatit*)).tw. OR eczema.tw. OR disseminated OR neurodermatit*.tw.)].

Study selection

Included were observati

SUBMITTER: Wang L 

PROVIDER: S-EPMC6990857 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature