Cortical Connectivity Moderators of Antidepressant vs Placebo Treatment Response in Major Depressive Disorder: Secondary Analysis of a Randomized Clinical Trial.

ABSTRACT:

Importance

Despite the widespread awareness of functional magnetic resonance imaging findings suggesting a role for cortical connectivity networks in treatment selection for major depressive disorder, its clinical utility remains limited. Recent methodological advances have revealed functional magnetic resonance imaging-like connectivity networks using electroencephalography (EEG), a tool more easily implemented in clinical practice.

Objective

To determine whether EEG connectivity could reveal neural moderators of antidepressant treatment.

Design, setting, and participants

In this nonprespecified secondary analysis, data were analyzed from the Establishing Moderators and Biosignatures of Antidepressant Response in Clinic Care study, a placebo-controlled, double-blinde

SUBMITTER: Rolle CE 

PROVIDER: S-EPMC6990859 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature