Global Epidemiologic Characteristics of Sexually Transmitted Infections Among Individuals Using Preexposure Prophylaxis for the Prevention of HIV Infection: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

Despite a global increase in sexually transmitted infections (STIs), there is limited focus and investment in STI management within HIV programs, in which risks for STIs are likely to be elevated.

Objective

To estimate the prevalence of STIs at initiation of HIV preexposure prophylaxis (PrEP; emtricitabine and tenofovir disoproxil fumarate) and the incidence of STIs during PrEP use.

Data sources

Nine databases were searched up to November 20, 2018, without language restrictions. The implementers of PrEP were also approached for additional unpublished data.

Study selection

Studies reporting STI prevalence and/or incidence among PrEP users were included.

Data extraction and synthesis

Data were extracted independently by at least 2 reviewers. The

SUBMITTER: Ong JJ 

PROVIDER: S-EPMC6991203 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature