Association of Blood Biomarkers With Acute Sport-Related Concussion in Collegiate Athletes: Findings From the NCAA and Department of Defense CARE Consortium.

ABSTRACT:

Importance

There is potential scientific and clinical value in validation of objective biomarkers for sport-related concussion (SRC).

Objective

To investigate the association of acute-phase blood biomarker levels with SRC in collegiate athletes.

Design, setting, and participants

This multicenter, prospective, case-control study was conducted by the National Collegiate Athletic Association (NCAA) and the US Department of Defense Concussion Assessment, Research, and Education (CARE) Consortium from February 20, 2015, to May 31, 2018, at 6 CARE Advanced Research Core sites. A total of 504 collegiate athletes with concussion, contact sport control athletes, and non-contact sport control athletes completed clinical testing and blood collection at preseason baseline, the ac

SUBMITTER: McCrea M 

PROVIDER: S-EPMC6991302 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature