Ontology highlight
ABSTRACT:
SUBMITTER: Malinverni D
PROVIDER: S-EPMC6992422 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Malinverni Duccio D Barducci Alessandro A
Entropy (Basel, Switzerland) 20191116 11
Extracting structural information from sequence co-variation has become a common computational biology practice in the recent years, mainly due to the availability of large sequence alignments of protein families. However, identifying features that are specific to sub-classes and not shared by all members of the family using sequence-based approaches has remained an elusive problem. We here present a coevolutionary-based method to differentially analyze subfamily specific structural features by ...[more]