Micronutrients in critically ill patients with severe acute kidney injury - a prospective study.

ABSTRACT: Malnutrition is common in patients with acute kidney injury (AKI) and the risk of mortality is high, especially if renal replacement therapy is needed. Between April 2013 through April 2014, we recruited critically ill adult patients (≥18 years) with severe AKI in two University hospitals in London, UK, and measured serial plasma concentrations of vitamin B₁, B₆, B₁₂, C and D, folate, selenium, zinc, copper, iron, carnitine and 22 amino acids for six consecutive days. In patients receiving continuous renal replacement therapy (CRRT), the concentrations of the same nutrients in the effluent were also determined. CRRT patients (n = 31) had lower plasma concentrations of citrulline, glutamic acid and carnitine at 24 hrs after enrolment and significantly lower

SUBMITTER: Ostermann M 

PROVIDER: S-EPMC6992767 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature