Prognostic value of pre-treatment Naples prognostic score (NPS) in patients with osteosarcoma.

ABSTRACT: BACKGROUND:This study aimed to evaluate the clinical significance of pre-treatment Naples prognostic score (NPS) in patients with osteosarcoma. METHODS:The clinical data of 133 osteosarcoma patients between January 2011 and February 2018 in our hospital was retrospectively collected and analyzed. NPS was calculated from four parameters, including serum albumin level, serum total cholesterol (TC), lymphocyte-to-monocyte ratio (LMR), and neutrophil-to-lymphocyte ratio (NLR). Patients were divided into three groups (group 1-3) based on NPS. The relationships between NPS and clinical features, overall survival (OS), and progression-free survival (PFS) were analyzed. Two prediction models based on NPS and clinical parameters were developed: clinical parameters model (model A), and the combined

SUBMITTER: Yang Q 

PROVIDER: S-EPMC6993441 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature