The Clinical Burden of Clostridioides difficile in Ontario, Canada.

ABSTRACT:

Background

To understand the clinical burden of Clostridioides difficile infection (CDI), we analyzed health outcome data from Ontario, Canada for CDI associated with and manifested in acute care hospitals (ACH), long-term care facilities (LTCF), the community, or ACH-associated with community-onset.

Methods

We performed a retrospective analysis using individual-level data from Ontario databases (April 1, 2005 to March 31, 2015), identifying CDI cases ≥18 years requiring hospitalization, and stratifying into cohorts based on association and onset location. Cohort members were matched to controls on demographics and medical conditions at onset, for outcomes including 30- and 180-day all-cause mortality and rehospitalization.

Results

We stratified 22 617 individu

SUBMITTER: Pereira JA 

PROVIDER: S-EPMC6993863 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature