A virtual molecular tumor board to improve efficiency and scalability of delivering precision oncology to physicians and their patients.

ABSTRACT:

Objectives

Scalable informatics solutions that provide molecularly tailored treatment recommendations to clinicians are needed to streamline precision oncology in care settings.

Materials and methods

We developed a cloud-based virtual molecular tumor board (VMTB) platform that included a knowledgebase, scoring model, rules engine, an asynchronous virtual chat room and a reporting tool that generated a treatment plan for each of the 1725 patients based on their molecular profile, previous treatment history, structured trial eligibility criteria, clinically relevant cancer gene-variant assertions, biomarker-treatment associations, and current treatment guidelines. The VMTB systematically allows clinician users to combine expert-curated data and structured data from clinical ch

SUBMITTER: Pishvaian MJ 

PROVIDER: S-EPMC6994017 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature